Therapeutic Options for Hidradenitis Suppurativa: An Update submitted: Mar 20, 2020; Accepted: May 18, 2020; Published online: Jun 3, 2020


Hasan Alghamdi


Hidradenitis suppurativa (HS) is a chronic skin condition with severe, deep inflammatory lesions, also referred to as acne inversa. Intertriginous regions, such as the axillae, groins (genital, anal, and perianal areas), infra- and intermammary skin, and buttocks are typically affected, although other areas (e.g., neck nape and lower abdominal fold) might also be affected. Painful nodules and leaking sinuses often affect patients with serious conditions, exuding fluid that sometimes smells, and many patients fear that these new lesions might burst at any moment, requiring incision and drainage, corticosteroid, or surgical injection. Topical lotion of clindamycin or cream of resorcinol can be useful long-term treatments in mild disease, while tetracycline is a first-line systemic option. While antibiotics can help reduce inflamed lesions, recurrence is common after discontinuation.

If patients do not respond well to these standard medical procedures, then using biologics such as adalimumab or infliximab would be the next step. Anti-inflammatory drugs, such as fumarate, dapsone, and cyclosporine, are also prescribed for HS. Surgical procedures are also necessary for healing, particularly when the sinuses or scars are present.

The clinical staging system of HS and the desires of patients should be used as the basis for every therapy.


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Hidradenitis suppurativa, Acne inversa, Clindamycin, Rifampicin, Infliximab

How to Cite
Alghamdi, H. (2020). Therapeutic Options for Hidradenitis Suppurativa: An Update: submitted: Mar 20, 2020; Accepted: May 18, 2020; Published online: Jun 3, 2020. Advances in Medicine and Medical Research, 3(1), 109-118.
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